If the intake and exhaust are in the same room the room pressure will remain neutral. it will not suck air in from another room.
If I were designing your layout I'd put the filter at the intake of the blower on one end of the room and use the ducting as exhaust and duct it to the other side of the room (as practical). That way dirty air goes though the filter first, then "clean" air continues through the blower and out the duct. By having the exhaust on the other side of the room you create a cross flow that guides airborne dust back at the filter. The exhaust is a much more powerful "air mover" then the intake is.
duct size should be dictated by the blower's CFM rating and the desired air velocity from the exhaust duct.
If I were designing your layout I'd put the filter at the intake of the blower on one end of the room and use the ducting as exhaust and duct it to the other side of the room (as practical). That way dirty air goes though the filter first, then "clean" air continues through the blower and out the duct. By having the exhaust on the other side of the room you create a cross flow that guides airborne dust back at the filter. The exhaust is a much more powerful "air mover" then the intake is.
duct size should be dictated by the blower's CFM rating and the desired air velocity from the exhaust duct.
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