I am a supporter of nitrogen fill. I work for a heavy equipment dealer and all of our rubber tire machines have nitrogen fill from the factory. Believe me, the engineers at the manufacturer would not specify it if they didn't see the value. This is not a gimmick to generate more sales, in fact most of our customers have no idea that their tires are nitrogen filled.
The advantage of nitrogen fill is not so much getting rid of the oxygen as it is getting rid of the moisture. As Loring points out, Boyle's laws don't work dramatically differently between oxygen and nitrogen. But the moisture in compressed air condenses on your wheels and the inside of your tires during the night, then when your tires heat up while driving it flashes into steam. This phase change from fluid to gas is what causes the change in pressure.
Nitrogen is extremely dry, no moisture. With no moisture and no oxygen, the inside of your steel wheels don't rust and the pressure stays much more stable. Also the wheels can become extremely hot during heavy braking. Nitrogen will not support combustion on the inside of the tire. Another (minor) benefit is it slows oxidation on the inside of the tire. True, the outside of the tire is also oxidizing, but the inside of an air-filled tire is filled with air at about 2 1/2 times the outside pressure.
From personal experience, I regularly (every few months) had to adjust the pressure on my air-filled tires. I've never had to adjust my nitrogen-filled tires except when I have had a puncture. Once the tire was repaired and refilled with nitrogen I never had to touch it again.
The advantage of nitrogen fill is not so much getting rid of the oxygen as it is getting rid of the moisture. As Loring points out, Boyle's laws don't work dramatically differently between oxygen and nitrogen. But the moisture in compressed air condenses on your wheels and the inside of your tires during the night, then when your tires heat up while driving it flashes into steam. This phase change from fluid to gas is what causes the change in pressure.
Nitrogen is extremely dry, no moisture. With no moisture and no oxygen, the inside of your steel wheels don't rust and the pressure stays much more stable. Also the wheels can become extremely hot during heavy braking. Nitrogen will not support combustion on the inside of the tire. Another (minor) benefit is it slows oxidation on the inside of the tire. True, the outside of the tire is also oxidizing, but the inside of an air-filled tire is filled with air at about 2 1/2 times the outside pressure.
From personal experience, I regularly (every few months) had to adjust the pressure on my air-filled tires. I've never had to adjust my nitrogen-filled tires except when I have had a puncture. Once the tire was repaired and refilled with nitrogen I never had to touch it again.


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